
Thermo Fisher Scientific P311 protein Polyclonal Antibody
P311 단백질을 인식하는 토끼 폴리클로날 항체로, Western blot, IHC, ICC, ELISA 등 다양한 응용에 적합합니다. 인간, 생쥐, 랫트 시료에 반응하며 Protein A로 정제된 고순도 항체입니다. 세포 분화 및 신경 기능 연구에 활용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:300–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:400 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human P311 (amino acids 25–68) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
P311 (also known as C5orf13, D4S114, PTZ17, or PRO1873) is a 68-amino-acid cytoplasmic protein involved in cellular differentiation, neural function, and axonal regeneration. It is primarily found in the granular layer of the cerebellum and expressed at lower levels in hippocampus, olfactory bulb, kidney, liver, and heart. Ectopic expression of P311 enhances glioma motility. In mice, P311 is enriched in the superficial cortical layers and striatum at E20 and in germinal zones at E17. P311 interacts with Filamin 1, regulates retinoic acid lipid-droplet biogenesis, and promotes fibroblast-to-myofibroblast differentiation. Phosphorylation at Ser-59 reduces P311 stability. The gene encoding P311 maps to human chromosome 5q22.1.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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