Thermo Fisher Scientific PHF20 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.2-1 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide directed towards the C-terminal of human PHF20 (aa 861-910). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PHF20,uniProtId:Q9BVI0-1,ncbiNodeId:9606,antigenRange:861-910,antigenLength:1012,antigenImageFileName:PA5-41151_PHF20_Q9BVI0-1_Rabbit.svg,antigenImageFileNamePDP:PA5-41151_PHF20_Q9BVI0-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS with 2% sucrose

Contains

0.09% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2605701

Product Specific Information

Peptide sequence: GSALDDAVNP LHENGDDSLS PRLGWPLDQD RSKGDSDPKP GSPKVKEYVS

Sequence homology: Cow: 92%; Guinea Pig: 83%; Horse: 83%; Human: 100%; Pig: 92%; Rabbit: 92%

Target Information

Methyllysine-binding protein, component of the MOF histone acetyltransferase protein complex. Not required for maintaining the global histone H4 Lys-16 acetylation (H4K16ac) levels or locus specific histone acetylation, but instead works downstream in transcriptional regulation of MOF target genes. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. Contributes to methyllysine-dependent p53/TP53 stabilization and up-regulation after DNA damage.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.