Thermo Fisher Scientific LDOC1 Polyclonal Antibody
Rabbit polyclonal antibody targeting human LDOC1. Recognizes recombinant LDOC1 protein (aa 23–69). Suitable for research use in studying NF-κB–mediated transcriptional regulation and tumor suppressor mechanisms. Supplied in liquid form, 0.1 mg/mL, stor...
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Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human LDOC1 (amino acids 23–69) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2643329 |
Product Specific Information
Immunogen sequence:
NSQLMEQLRL LVCERASLLR QVRPPSCPVP FPETFNGESS RLPEFIV
Highest antigen sequence identity to orthologs:
- Mouse: 77%
- Rat: 74%
Target Information
LDOC1 contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is down-regulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kappa B (NF-kappaB). The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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