
Thermo Fisher Scientific GSS Polyclonal Antibody
Thermo Fisher Scientific의 GSS Polyclonal Antibody는 인간 GSS 단백질을 인식하는 토끼 유래 다클론 항체입니다. Western blot, IHC, ICC/IF에 사용 가능하며, 항원 친화 정제 방식으로 높은 특이성과 재현성을 제공합니다. 연구용으로만 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human GSS. Recombinant protein control fragment (Product #RP-105125) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2662893 |
Product Specific Information
Immunogen sequence:
ISEKGSLDQDR RLFVDGQEIA VVYFRDGYMP RQYSLQNWEA RLLLERSHAA KCPDIATQLA GTKKVQQELS RPGMLEMLLP G
Highest antigen sequence identity to the following orthologs:
- Mouse: 82%
- Rat: 83%
Target Information
Glutathione plays a critical role in protecting cells from oxidative damage by free radicals, detoxifying xenobiotics, and facilitating membrane transport.
The GSS protein acts as a homodimer to catalyze the ATP-dependent conversion of gamma-L-glutamyl-L-cysteine to glutathione, the second step in glutathione biosynthesis.
Defects in this gene can cause glutathione synthetase deficiency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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