Thermo Fisher Scientific PCDH1 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:3,000

Immunocytochemistry (ICC/IF)

• Tested Dilution: 1:100–1:1,000

Product Specifications

Product Specific Information

• Recommended positive controls: A431
• Predicted reactivity: Mouse (98%), Chicken (88%), Bovine (97%)
• Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

Protocadherin 1 (PCDH1), also known as cadherin-like protein 1, is a transmembrane protein involved in cell-cell adhesion. It belongs to the delta1-protocadherin group (including PCDH1, PCDH7, PCDH9, PCDH11X/Y), characterized by seven extracellular cadherin repeats, a transmembrane domain, and a cytoplasmic domain. It exists in two isoforms (short and long) and shows tissue-specific and temporal expression patterns. PCDH1 plays roles in early development and mature tissues, being expressed in brain, spinal cord, peripheral ganglia, inner ear, hair follicles, kidney, reproductive organs, prostate, and seminal gland in mice. It is a susceptibility gene for Bronchial Hyperresponsiveness in humans and is expressed on human pluripotent stem cells.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.