Thermo Fisher Scientific Human N4BP1 Synthetic Peptide
인간 N4BP1 단백질의 N-말단 근처 18개 아미노산 서열로 구성된 합성 펩타이드. PA5-21099 항체의 블로킹 펩타이드로 사용 가능. 액상형, PBS(pH 7.2) 버퍼에 0.1% BSA 및 0.02% sodium azide 함유. -20°C 보관.
- 카탈로그번호
- PEP1213
- 판매단위
- pk
카탈로그
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to an 18 amino acid sequence near the amino terminus of human N4BP1.
PEP-1213 can be used as a blocking peptide with polyclonal antibody PA5-21099.
Target Information
Nedd4-binding partner-1 (N4BP1) is a developmentally expressed protein interactor and monoubiquitylation substrate of Nedd4, a HECT domain-containing ubiquitin ligase that mediates ubiquitylation and proteasome degradation of target proteins. It may play a fundamental role in embryonic processes.
N4BP1 can undergo Nedd4-mediated polyubiquitylation and proteosomal degradation. It also functions as a negative regulator of AIF4 (also known as ITCH or Atrophin-1), an E3-ubiquitin ligase, by interacting with the second WW domain of AIF4 and impairing ubiquitination of substrates.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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