Thermo Fisher Scientific MT-ND5 Polyclonal Antibody
Rabbit polyclonal antibody targeting human MT-ND5 protein. Validated for WB, IHC(P), and Flow Cytometry. High specificity and sensitivity. Suitable for mitochondrial research and complex I studies. For research use only.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000 |
| Flow Cytometry (Flow) | 1:10–1:50 |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide between amino acids 544–570 from the C-terminal region of human ND5 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C and avoid freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2718355 |
Target Information
A small number of Complex I subunits are products of mitochondrial genes (subunits 1–7), while the remainder are nuclear encoded and imported from the cytoplasm. NADH dehydrogenase subunit 5 (ND5) is a component of the hydrophobic protein fragment of Complex I. Mutations in the ND5 gene are implicated in mitochondrial neurogastrointestinal encephalomyopathy, an autosomal recessive multisystem disorder characterized by elevated circulating thymidine and deoxyuridine levels.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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