Thermo Fisher Scientific Oxycodone Polyclonal Antibody
Oxycodone(N)-BSA를 면역원으로 한 Sheep Polyclonal Antibody로 ELISA에 적합. 높은 특이성과 감도를 가지며 Oxycodone 검출에 활용 가능. 액상 형태로 제공되며 PBS buffer(pH 7.2)에 0.09% sodium azide 포함. -20°C 보관, 동결-해동 반복 회피 필요.
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Applications
- ELISA (ELISA)
Tested Dilution: 5–10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Chemical |
| Host / Isotype | Sheep / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Oxycodone(N)-BSA |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Purified |
| Storage buffer | PBS, pH 7.2 |
| Contains | 0.09% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1090592 |
Product Specific Information
- Working Concentration: 1/8K
- Sensitivity: 10 ng/mL Oxycodone produces 39% inhibition in a competitive ELISA employing Oxycodone(N) polyclonal antibody.
Target Information
Oxycodone is a semi-synthetic, morphine-like opioid alkaloid with analgesic activity. It exerts its analgesic effect by binding to mu-receptors in the central nervous system (CNS), mimicking endogenous opioids. This binding stimulates the exchange of GTP for GDP on the G-protein complex and inhibits adenylate cyclase, reducing cAMP production. Consequently, the release of nociceptive neurotransmitters such as substance P, GABA, dopamine, acetylcholine, and noradrenaline is inhibited. Oxycodone also inhibits the release of vasopressin, somatostatin, insulin, and glucagon, and modulates ion channels resulting in neuronal hyperpolarization and reduced excitability.
[National Center for Biotechnology Information. PubChem Compound Database; CID=5284603]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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