Thermo Fisher Scientific RPL7A Polyclonal Antibody
Rabbit polyclonal antibody against human RPL7A protein. Validated for immunocytochemistry (ICC/IF) with a dilution range of 0.25–2 µg/mL. Supplied as an unconjugated liquid at 0.1 mg/mL concentration. Suitable for detecting ribosomal protein L7A in res...
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Category | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human RPL7A. Recombinant protein control fragment (Product # RP-100028) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2790992 |
Product Specific Information
Immunogen sequence:
EAIRTNYNDR YDEIRRHWGG NVLGPKSVAR IAKLE
Target Information
Cytoplasmic ribosomes, organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins.
This gene encodes a ribosomal protein that is a component of the 60S subunit and belongs to the L7AE family of ribosomal proteins. It can interact with nuclear hormone receptors, including the thyroid hormone receptor, and inhibit their ability to transactivate by preventing their DNA binding.
This gene is part of the surfeit gene cluster, co-transcribed with several small nucleolar RNA genes (U24, U36a, U36b, U36c). It can rearrange with the trk proto-oncogene to form the chimeric oncogene trk-2h, producing an oncoprotein combining the N terminus of ribosomal protein L7A with the receptor tyrosine kinase domain of trk.
As typical for ribosomal protein genes, multiple processed pseudogenes of this gene are dispersed throughout the genome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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