Thermo Fisher Scientific OASL Polyclonal Antibody
OASL 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, Western blot에 최적화되어 있습니다. 인간 Oasl1 중간 영역을 면역원으로 사용하였으며, 액상 형태로 제공됩니다. 다양한 종에서 높은 상동성을 보이며 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB): 1.0 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of human Oasl1 (aa 420–469) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2690058 |
Product Specific Information
This target displays homology in the following species:
Dog: 100%; Guinea Pig: 100%; Horse: 92%; Human: 100%; Mouse: 100%; Rabbit: 85%; Rat: 100%
Target Information
2-prime,5-prime oligoadenylates (2-5As) bind to and activate RNase L, leading to degradation of RNA and inhibition of protein synthesis. 2-5As are produced by 2-5A synthetases (OASs), a highly-conserved family of interferon-induced enzymes.
The predicted 514-amino acid human p59OASL (2-5A synthetase-like) protein shares a highly conserved N-terminal domain with other OASs. The C-terminal portion of p59OASL contains two ubiquitin-like domains. p59OASL is expressed in most tissues, with the highest levels in hematopoietic tissues, colon, and stomach.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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