Thermo Fisher Scientific RTCA Polyclonal Antibody
Thermo Fisher Scientific의 RTCA Polyclonal Antibody는 Rat 단백질을 인식하는 Rabbit IgG 기반 항체입니다. Western blot에 적합하며, 합성 펩타이드 면역원으로 제작되었습니다. 액상 형태로 제공되며 -20°C에서 보관합니다. 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB): Tested dilution 1.0 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of rat Rtcd1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2689519 |
Product Specific Information
This target displays homology in the following species:
Cow: 93% · Dog: 100% · Guinea Pig: 100% · Horse: 93% · Human: 100% · Mouse: 86% · Rabbit: 100% · Rat: 93%
Target Information
RTCD1 catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA.
The enzyme mechanism involves three steps:
- Adenylation of the enzyme by ATP
- The enzyme acts on RNA-N3'P to produce RNA-N3'PP5'A
- A non-catalytic nucleophilic attack by the adjacent 2'-hydroxyl on the phosphorus in the diester linkage to produce the cyclic end product
The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing. There are two named isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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