Thermo Fisher Scientific KIF14 Polyclonal Antibody
KIF14 단백질을 표적으로 하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. WB, IHC, ICC, IP 등 다양한 응용에 적합. 고순도 액상 형태로 제공되며 4°C에서 보관. 세포 내 미세소관 관련 연구 및 암 관련 단백질 분석에 활용 가능.
- 카탈로그번호
- A300912Ax (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific KIF14 Polyclonal Antibody
Thermo Fisher Scientific KIF14 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:200–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:200–1:1,000 |
| Immunoprecipitation (IP) | 2–5 µg/mg lysate |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1600 and the C-terminus (residue 1648) of human Kinesin Family Member 14 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Application Note:
- For ICC, formaldehyde fixation and Triton-X 100 permeabilization are recommended.
- For IHC, epitope retrieval with Tris-EDTA pH 9.0 is recommended for FFPE tissue sections.
Target Information
KIF14 encodes a member of the kinesin-3 superfamily of microtubule motor proteins. These proteins are involved in vesicle transport, chromosome segregation, mitotic spindle formation, and cytokinesis.
In HeLa-S3 and 293T cells, KIF14 localizes to the cytoplasm during interphase, to spindle poles and microtubules during mitosis, and to the midbody during cytokinesis.
Its motor domain exhibits microtubule-dependent ATPase activity. Knockdown of KIF14 leads to failed cytokinesis and multinucleated cells.
KIF14 is identified as a potential oncogene in breast, lung, ovarian cancers, retinoblastomas, and gliomas.
Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.