Thermo Fisher Scientific TMC7 Polyclonal Antibody
인간 TMC7 단백질에 특이적인 Rabbit Polyclonal 항체로, IHC(P) 및 ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며 액상 형태로 제공. 연구용으로만 사용되며 장기 보관 시 -20°C에서 냉동 보관 권장.
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Thermo Fisher Scientific TMC7 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human TMC7. Recombinant protein control fragment (Product #RP-90832) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.15 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2648533 |
Product Specific Information
Immunogen sequence:
LDSSCFSSPP VNFLQELPSY RSIARRRTTV HSRDKQSGTL LKPTDSYSSQ LEDRIAENLS SHSLRNYALN ISEKRRLRDI QETQMKYLSE WDQWKRYSSK SWKRFLEKAR EMTTHLE
Highest antigen sequence identity to orthologs:
- Mouse: 86%
- Rat: 85%
Target Information
TMC7 (Transmembrane channel-like protein 7) is a 723 amino acid protein belonging to the TMC family.
All TMC genes encode transmembrane proteins with intracellular amino and carboxy termini and at least eight membrane-spanning domains.
TMC7 may function as an ion channel or transporter.
The gene encoding TMC7 maps to human chromosome 16, which contains over 900 genes (~3% of the human genome).
Mutations in related genes on chromosome 16 can lead to disorders such as giant axonal neuropathy, Rubinstein-Taybi syndrome, and Crohn’s disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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