Thermo Fisher Scientific MYT1L Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human MYT1L. Recombinant protein control fragment (Product #RP-101577). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:MYT1L,uniProtId:Q9UL68-1,ncbiNodeId:9606,antigenRange:415-488,antigenLength:1186,antigenImageFileName:PA5-84447_MYT1L_Q9UL68-1_Rabbit.svg,antigenImageFileNamePDP:PA5-84447_MYT1L_Q9UL68-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2791598

Product Specific Information

Immunogen sequence: VNSDRSEEVF DMTKGNLTLL EKAIALETER AKAMREKMAM EAGRRDNMRS YEDQSPRQLP GEDRKPKSSD SHVK

Target Information

MYT1L, myelin transcription factor 1 family, to which the myelin transcription factor 1-like protein (MYT1L) belongs, is expressed primarily in the developing central nervous system and recruits histone deacetylase (HDAC) to regulate neural transcription. Both MYT1L and the related protein MYT1 interact with SIN3B, a protein that mediates transcriptional repression by binding to HDACs, suggesting that the MYT1 family favor the silencing of genes during neural development. Recent studies suggest that polymorphisms of MYT1L may be associated with schizophrenia.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.