Thermo Fisher Scientific WNK4 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human WNK4. Recombinant protein control fragment (Product #RP-91428). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:WNK4,uniProtId:Q96J92-1,ncbiNodeId:9606,antigenRange:1005-1138,antigenLength:1243,antigenImageFileName:PA5-53437_WNK4_Q96J92-1_Rabbit.svg,antigenImageFileNamePDP:PA5-53437_WNK4_Q96J92-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2649659

Product Specific Information

Immunogen sequence: ISEEGKPQLV GRFQVTSSKE PAEPLPLQPT SPTLSGSPKP STPQLTSESS DTEDSAGGGP ETREALAESD RAAEGLGAGV EEEGDDGKEP QVGGSPQPLS HPSPVWMNYS YSSLCLSSEE SESSGEDEEF WAEL

Highest antigen sequence identity to the following orthologs: Mouse - 85%, Rat - 87%.

Target Information

This gene encodes a member of the WNK family of serine-threonine protein kinases. The kinase is part of the tight junction complex in kidney cells, and regulates the balance between NaCl reabsorption and K(+) secretion. The kinase regulates the activities of several types of ion channels, cotransporters, and exchangers involved in electrolyte flux in epithelial cells. Mutations in this gene result in pseudohypoaldosteronism type IIB.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.