Thermo Fisher Scientific ABCG5 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human ABCG5. Recombinant protein control fragment (Product #RP-91210). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:ABCG5,uniProtId:Q9H222-1,ncbiNodeId:9606,antigenRange:249-372,antigenLength:651,antigenImageFileName:PA5-53439_ABCG5_Q9H222-1_Rabbit.svg,antigenImageFileNamePDP:PA5-53439_ABCG5_Q9H222-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.3 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2637542

Product Specific Information

Immunogen sequence: IHQPRSELFQ LFDKIAILSF GELIFCGTPA EMLDFFNDCG YPCPEHSNPF DFYMDLTSVD TQSKEREIET SKRVQMIESA YKKSAICHKT LKNIERMKHL KTLPMVPFKT KDSPGVFSKL GVLL

Highest antigen sequence identity to the following orthologs: Mouse - 81%, Rat - 81%.

Target Information

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. The protein encoded by this gene functions as a half-transporter to limit intestinal absorption and promote biliary excretion of sterols. It is expressed in a tissue-specific manner in the liver, colon, and intestine. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG8. Mutations in this gene may contribute to sterol accumulation and atherosclerosis, and have been observed in patients with sitosterolemia.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.