Thermo Fisher Scientific H3K79me3 Polyclonal Antibody
H3K79me3에 특이적인 Rabbit Polyclonal 항체로, Western blot, IHC, ICC, IP, ChIP 등 다양한 응용에 사용 가능. 인간 및 생쥐 시료 반응성. 고순도 친화 크로마토그래피 정제, -20°C 보관. 연구용 전용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:20–1:50 |
| Immunoprecipitation (IP) | 1:20–1:50 |
| ChIP assay (ChIP) | 1:20–1:50 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human HIST3H3 (Accession Q16695), corresponding to amino acid residues I63–V90 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2815925 |
Product Specific Information
This antibody detects endogenous levels of Tri-Methyl-Histone H3 only when methylated at Lys79.
Target Information
Histone H3 is a DNA-binding protein present in the chromatin of all eukaryotic cells. Together with other core histones, it forms nucleosomes and plays a central role in transcription regulation, DNA repair, replication, and chromosomal stability. Post-translational modifications of histone H3, such as methylation, acetylation, and phosphorylation, influence chromatin structure and gene expression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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