Thermo Fisher Scientific TRAF2 Polyclonal Antibody
Human TRAF2 단백질에 특이적인 Rabbit Polyclonal Antibody로, Western Blot에 적합하며 보존제가 포함되지 않은 액상 형태입니다. Protein A 및 항원 친화 크로마토그래피로 정제되었으며, 장기 보관 시 -20°C에서 보관을 권장합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to the C-terminus of Human TRAF2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C, avoiding freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2788755 |
Product Specific Information
- Preservative-free formulation.
- It is recommended to add sodium azide (final concentration 0.05%–0.1%) to prevent contamination.
- Specific for Human TRAF2.
Target Information
Tumor necrosis factor (TNF) receptor-associated factors (TRAFs) are adaptor proteins that link the TNF receptor superfamily to various signaling pathways, playing key roles in regulating cell death and stress responses.
TRAF proteins possess a conserved domain that mediates interactions with cell receptors and other TRAFs, triggering distinct signaling cascades. TRAF2 and TRAF3 bind directly to CD40, a receptor crucial for NF-κB activation in B lymphocytes. TRAF2 also participates in CD40 signaling in nonhematopoietic cells and interacts with lymphotoxin-beta receptor (LTβR) along with TRAF3 and apoptosis regulators such as cIAP1 and Smac.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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