Thermo Fisher Scientific BCoR Polyclonal Antibody
BCoR 단백질을 인식하는 Thermo Fisher Scientific의 다클론 항체로, Western blot 및 Immunoprecipitation에 적합합니다. Rabbit IgG 기반의 액상 비결합 항체이며, 4°C에서 보관합니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–5 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1705 and 1755 of human BCL6 co-repressor |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
Target Information
Transcriptional corepressor. May specifically inhibit gene expression when recruited to promoter regions by sequence-specific DNA-binding proteins such as BCL6 and MLLT3.
This repression may be mediated at least in part by histone deacetylase activities which can associate with this corepressor.
Involved in the repression of TFAP2A; impairs binding of BCL6 and KDM2B to TFAP2A promoter regions.
Via repression of TFAP2A acts as a negative regulator of osteo-dentiogenic capacity in adult stem cells; the function implies inhibition of methylation on histone H3 Lys-4 (H3K4me3) and Lys-36 (H3K36me2).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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