Thermo Fisher Scientific TTI2 Polyclonal Antibody
Human TTI2 단백질에 특이적인 Rabbit Polyclonal Antibody로 Western blot, IHC, ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제된 액상 시약이며, PBS 기반 버퍼에 40% glycerol 포함. 연구용으로만 사용 가능.
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Thermo Fisher Scientific TTI2 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human TTI2. Recombinant protein control fragment (Product #RP-93783). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2649091 |
Product Specific Information
Immunogen sequence:
QEDSNLSEEL SHSAFGQAFS KILHCLARPE ARRGNVKDAV LKDLGDLIEA TGFDRLFEGT GARLRGMPET LGQVAKALEK Y
Antigen sequence identity (orthologs):
- Mouse: 52%
- Rat: 57%
Target Information
The DNA replication (origin) licensing system is necessary for duplicating the genome in each cell cycle. Geminin is a protein that prevents DNA replication by blocking the MCM complex incorporation into the prereplication complex (pre-RC). It is absent during G1 phase and accumulates during S, G2, and M phases of mitosis. It is degraded during the metaphase–anaphase transition, allowing replication to occur during subsequent cycles. Geminin also plays a role in maintaining the integrity of the male germline genome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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