Thermo Fisher Scientific PFKP Monoclonal Antibody (OTI1A11), TrueMAB

Applications and Tested Dilutions

Product Specifications

Product Specific Information

For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the γ-phosphate of ATP, onto an acceptor amino acid in a substrate protein. Through this mechanism, protein kinases mediate most signal transduction in eukaryotic cells, regulating metabolism, transcription, cell cycle progression, cytoskeletal rearrangement, cell movement, apoptosis, and differentiation.

The protein kinase family includes more than 500 gene products and is classified into 8 major groups based on catalytic domain sequences.
The AGC kinase group comprises 63 kinases, including:

• PKA & PKG (cyclic nucleotide-regulated kinases)
• PKC (diacylglycerol-activated/phospholipid-dependent kinases)
• RAC/Akt family
• ARK (G protein-coupled receptor kinases)
• RSK (ribosomal protein S6 kinases)

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.