Thermo Fisher Scientific USP7 Monoclonal Antibody (OTI1B2), TrueMAB

Applications and Tested Dilutions

Product Specifications

Product Specific Information

For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

USP7 (also known as HAUSP) is a ubiquitin-specific protease that removes ubiquitin from substrate proteins, thereby regulating their stability.
It acts as a direct antagonist of Mdm2, an E3 ligase responsible for p53 degradation, and thus contributes to p53 stabilization under stress conditions.
HAUSP may function as a tumor suppressor by protecting p53 from degradation, while also participating in oncogenic pathways involving Myc and E1A.
Its role in deubiquitination makes USP7 a key regulator in cellular stress responses and cancer biology.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.