Thermo Fisher Scientific PTP1B Polyclonal Antibody
Rabbit polyclonal antibody against PTP1B for WB, IHC, ELISA, and IP applications. Recognizes recombinant human PTP1B/PTPN1 protein. Supplied as liquid form, stored at -20°C. Suitable for research use only.
- 카탈로그번호
- PA5118220
- 판매단위
- pk
카탈로그
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:2,000–1:10,000 |
| ELISA | 1:25,000–1:50,000 |
| Immunoprecipitation (IP) | 0.2–1 µL/mg of lysate |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human PTP1B/PTPN1 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
Target Information
PTP1B (PTPN1) is a tyrosine-protein phosphatase that regulates the endoplasmic reticulum unfolded protein response. It mediates dephosphorylation of EIF2AK3/PERK, inactivating its kinase activity. PTP1B also participates in CKII- and p60c-src-induced signal transduction cascades, regulates the EFNA5-EPHA3 signaling pathway affecting cell reorganization and repulsion, and modulates hepatocyte growth factor receptor signaling through dephosphorylation of MET.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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