Thermo Fisher Scientific Cdc42EP3 Polyclonal Antibody
Rabbit polyclonal antibody recognizing human, mouse, and rat CDC42EP3 protein. Validated for Western blot applications. Supplied as liquid, 1 mg/mL, in PBS with 50% glycerol. For research use only.
- 카탈로그번호
- PA550002
- 판매단위
- pk
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Applications
- Western Blot (WB): 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from N-terminal of human CDC42EP3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2635455 |
Product Specific Information
The antibody detects endogenous levels of total CDC42EP3 / BORG2 protein.
Target Information
CDC42, a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with downstream effector proteins. The protein encoded by this gene is a member of the Borg family of CDC42 effector proteins, which contain a CRIB (Cdc42/Rac interactive-binding) domain. These proteins bind to and negatively regulate CDC42. CDC42EP3 can interact with CDC42 and ARHQ/TC10, and its expression in fibroblasts induces pseudopodia formation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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