Thermo Fisher Scientific PER3 Polyclonal Antibody
PER3 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, ICC 등 다양한 응용에 적합. 인간, 마우스, 랫트 시료에 반응하며, 고순도 친화 크로마토그래피 정제. PBS/glycerol 완충액에 보관되며, 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:200 |
| Immunocytochemistry / Immunofluorescence (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human PER3 (Accession P56645), corresponding to amino acid residues T952–H1002 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2852164 |
Product Specific Information
Antibody detects endogenous levels of total PER3.
Target Information
This gene is a member of the Period (PER) family and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. PER family genes encode components regulating circadian rhythms of locomotor activity, metabolism, and behavior. The gene is upregulated by CLOCK/ARNTL heterodimers but represses this upregulation via PER/CRY heterodimers in a feedback loop. Polymorphisms in this gene have been linked to sleep disorders. Multiple transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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