Thermo Fisher Scientific SSEA1 Monoclonal Antibody (28)
인간 CD15(SSEA1) 항원을 인식하는 마우스 단클론 항체로, IHC, Flow Cytometry, IP 등 다양한 응용에 사용 가능. 비결합형 액상 형태로 제공되며, 1 mg/mL 농도. PBS 용액에 보존제로 구성되어 있으며, 단기 4°C, 장기 -20°C 보관 권장.
- 카탈로그번호
- MA134583
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (PFA fixed) | Assay-dependent |
| Immunohistochemistry (Frozen) | Assay-dependent |
| Flow Cytometry | Assay-dependent |
| Immunoprecipitation | Assay-dependent |
| Miscellaneous PubMed | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Mouse / IgM |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 28 |
| Immunogen | Cell preparation: Monocytes, separated from other peripheral blood leucocytes (PBL) on fibronectin plates. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | IgG fraction |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1955089 |
Product Specific Information
MA1-34583 detects CD15 from human samples.
Target Information
CD15 (Lewis X, Le(x); stage specific embryonic antigen-1, SSEA-1) is a trisaccharide determinant (3-fucosyl-N-acetyllactosamine) expressed on several glycolipids, glycoproteins, and proteoglycans of various cell types such as granulocytes, mast cells, monocytes, macrophages, gastric mucosa cells, nervous system cells, and various tumor cells.
Variants include sialyl-Lewis x and sulphated Lewis x. Cells with high Le(x) expression exhibit strong calcium-dependent self-aggregation, relevant to processes such as embryo compaction and teratocarcinoma cell aggregation.
Sialyl-Le(x) and sialyl-Le(a) act as ligands of selectins. CD15 expression is often used to confirm diagnosis of Hodgkin’s disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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