Thermo Fisher Scientific BTNL2 Polyclonal Antibody
BTNL2 단백질을 인식하는 Thermo Fisher Scientific의 다클론 항체로, Western blot, IHC, ELISA 등에 사용 가능. 인간, 생쥐, 랫드 반응성. 고순도 친화 크로마토그래피 정제, 액상 형태로 제공. 연구용으로만 사용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 246–455 of human BTNL2 (NP_062548.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.61 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2854869 |
Product Specific Information
Immunogen sequence:
LKVNGPSQPI LVRVGEDIQL TCYLSPKANA QSMEVRWDRS HRYPAVHVYM DGDHVAGEQM AEYRGRTVLV SDAIDEGRLT LQILSARPSD DGQYRCLFEK DDVYQEASLD LKVVSLGSSP LITVEGQEDG EMQPMCSSDG WFPQPHVPWR DMEGKTIPSS SQALTQGSHG LFHVQTLLRV TNISAVDVTC SISIPFLGEE KIATFSLSGW
Target Information
BTNL2 (butyrophilin-like protein 2), also known as BTL-II, is a 455 amino acid single-pass type II membrane protein that acts as a negative regulator of T cell proliferation.
It is expressed in thymus, brain, kidney, heart, liver, small intestine, testis, ovary, pancreas, and leukocytes.
BTNL2 exists as at least six alternatively spliced isoforms encoded by a gene located on human chromosome 6.
Expression of BTNL2 isoform 3 is associated with susceptibility to sarcoidosis type 2 (SS2), an immune disorder that causes chronic inflammatory granulomatous lesions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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