Thermo Fisher Scientific BVES Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 241-360 of human BVES (NP_001186492.1). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:BVES,uniProtId:Q8NE79-1,ncbiNodeId:9606,antigenRange:241-360,antigenLength:360,antigenImageFileName:PA5-109460_BVES_Q8NE79-1_Rabbit.svg,antigenImageFileNamePDP:PA5-109460_BVES_Q8NE79-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.09% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2854871

Product Specific Information

Immunogen sequence: SEPFLYEIFR YLIGKDITNK LYSLNDPTLN DKKAKKLEHQ LSLCTQISML EMRNSIASSS DSDDGLHQFL RGTSSMSSLH VSSPHQRASA KMKPIEEGAE DDDDVFEPAS PNTLKVHQLP

Target Information

Blood vessel epicardial substance (BVES), also designated Popeye protein 1, is a transmembrane protein that plays a role in cell-cell interactions and adhesion, specifically at tight junctions. BVES is composed of an extracellular amino-terminus, three transmembrane domains and a cytoplasmic carboxyl-terminus. It is expressed in the developing coronary vascular system, specifically in the proepicardium, migrating epithelial epicardium, delaminated vasculogenic mesenchyme and vascular smooth muscle cells, where it functions to direct development in heart, epithelial and muscle cells during embryogenesis. BVES accumulates at points of cell-cell contact, such as filopodia and cell borders, and promotes adhesion prior to the arrival of E-cadherin.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.