Thermo Fisher Scientific FNTB Monoclonal Antibody (3A9)
FNTB 단백질을 인식하는 Thermo Fisher Scientific의 Mouse monoclonal antibody (Clone 3A9). Western blot, ICC/IF, ELISA에 적합하며, Human 시료 반응성이 확인됨. PBS buffer에 보존된 액상 형태로, -20°C에서 보관 권장.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| ELISA | 3 ng/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3A9 |
| Immunogen | FNTB (AAH20232, 1–437 a.a.) full-length recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MASPSSFTYY CPPSSSPVWS EPLYSLRPEH ARERLQDDSV ETVTSIEQAK VEEKIQEVFS SYKFNHLVPR LVLQREKHFH YLKRGLRQLT DAYECLDASR PWLCYWILHS LELLDEPIPQ IVATDVCQFL ELCQSPEGGF GGGPGQYPHL APTYAAVNAL CIIGTEEAYD IINREKLLQY LYSLKQPDGS FLMHVGGEVD VRSAYCAASV ASLTNIITPD LFEGTAEWIA RCQNWEGGIG GVPGMEAHGG YTFCGLAALV ILKRERSLNL KSLLQWVTSR QMRFEGGFQG RCNKLVDGCY SFWQAGLLPL LHRALHAQGD PALSMSHWMF HQQALQEYIL MCCQCPAGGL LDKPGKSRDF YHTCYCLSGL SIAQHFGSGA MLHDVVLGVP ENALQPTHPV YNIGPDKVIQ ATTYFLQKPV PGFEELKDET SAEPATD
Target Information
Eukaryotic cells contain three types of prenyltransferases that attach either a farnesyl group (15 carbons) or a geranylgeranyl group (20 carbons) in thioether linkage to C-terminal cysteine residues in various proteins. These posttranslational modifications enable membrane localization of proteins lacking transmembrane domains.
CAAX farnesyltransferase (FTase) transfers a farnesyl group from farnesyl pyrophosphate to cysteine residues at the fourth position from the C terminus in proteins ending with the CAAX box (C: cysteine; A: aliphatic amino acid; X: typically methionine or serine).
The beta subunit gene of CAAX farnesyltransferase (FNTB) is located at 14q23–q24, identified via Southern blot hybridization, PCR analyses of human/Chinese hamster somatic cell hybrid lines, and fluorescence in situ hybridization.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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