Thermo Fisher Scientific IGSF3 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human IGSF3. Recombinant protein control fragment (Product #RP-102708). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:IGSF3,uniProtId:O75054-1,ncbiNodeId:9606,antigenRange:587-725,antigenLength:1194,antigenImageFileName:PA5-83319_IGSF3_O75054-1_Rabbit.svg,antigenImageFileNamePDP:PA5-83319_IGSF3_O75054-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2790475

Product Specific Information

Immunogen sequence: VGTVEFHDLV TFTRDGGVQW GDRSSSFRTR TAIEKAESSN NVRLSISRAS DTEAGKYQCV AELWRKNYNN TWTRLAERTS NLLEIRVLQP VTKLQVSKSK RTLTLVENKP IQLNCSVKSQ TSQNSHFAVL WYVHKPSDA

Target Information

IGSF3 (immunoglobulin superfamily, member 3), also known as V8 or EWI-3, is a 1,214 amino acid protein. Widely expressed with predominant expression in kidney, placenta and lung, IGSF3 localizes to the membrane and contains an N-terminal signal peptide, eight immunoglobulin (Ig) domains and a transmembrane segment. IGSF3 exhibits strong sequence and structural similarity to CD101 (32% identity), a leukocyte surface protein with seven Ig domains that is believed to play a role in T-cell activation. Despite the structural similarities between IGSF3 and CD101, IGSF3 is not expressed in peripheral blood lymphocytes and does not appear to participate in an immune function.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.