
Thermo Fisher Scientific CIS Recombinant Superclonal Antibody
인간 CIS 단백질을 인식하는 Thermo Fisher Scientific의 재조합 Superclonal 항체. 폴리클로날의 민감도와 모노클로날의 특이성을 결합한 고재현성 항체로 WB 및 ICC/IF에 적합. Expi293 시스템에서 생산되어 높은 일관성과 감도를 제공.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5–1 µg/mL |
| Immunocytochemistry (ICC/IF) | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | Expi293 |
| Class | Recombinant Superclonal |
| Type | Antibody |
| Immunogen | Peptide corresponding to Human CIS (aa 1–258) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.2 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2532775 |
Product Specific Information
This antibody is predicted to react with Monkey, Pig, Bovine, Rat, and Mouse.
Recombinant rabbit Superclonal™ antibodies are unique offerings from Thermo Fisher Scientific. They combine multiple different recombinant monoclonal antibodies, offering the sensitivity of polyclonal antibodies and the specificity of monoclonal antibodies, with the consistency only achievable from recombinant production.
While functionally similar to polyclonal antibodies—recognizing multiple epitope sites and providing higher detection sensitivity for low-abundance targets—Superclonal™ antibodies have a defined mixture of light and heavy chains, ensuring reproducibility across lots.
Note: Formerly called “Recombinant Polyclonal Antibody”, now rebranded as “Recombinant Superclonal™ Antibody”. The physical product and performance remain unchanged.
Target Information
CIS (Cytokine-Inducible SH2-containing protein) contains SH2 and SOCS box domains and belongs to the cytokine-induced STAT inhibitor (CIS/SOCS/SSI) family. These proteins act as cytokine-inducible negative regulators of cytokine signaling. Expression can be induced by IL2, IL3, GM-CSF, and EPO in hematopoietic cells. Proteasome-mediated degradation of CIS is involved in erythropoietin receptor inactivation. Multiple transcript variants encoding different isoforms have been identified.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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