Thermo Fisher Scientific CDCA7L Monoclonal Antibody (OTI1A12), TrueMAB
CDCA7L 단백질을 인식하는 Mouse IgG1 단일클론 항체로, WB 및 IHC(P) 실험에 적합합니다. 인간 시료에 반응하며, 고순도 친화 크로마토그래피 정제 제품입니다. 1 mg/mL 농도의 액상 형태로, -20°C에서 보관합니다.
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- TA802918
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1A12 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–337 of human CDCA7L produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Cell division cycle-associated 7-like protein (CDCA7L, also known as RAM2) is a transcription factor involved in transcriptional regulation and apoptotic signaling pathways. It acts as a repressor that inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to its promoter. CDCA7L plays an oncogenic role in mediating the full transforming effect of MYC in medulloblastoma cells. It may act downstream of P38-kinase and BCL-2, but upstream of CASP3/caspase-3, CCND1/cyclin D1, and E2F1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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