
Thermo Fisher Scientific TSN Polyclonal Antibody
Human 및 Mouse 반응성을 가진 Rabbit Polyclonal Antibody로, Western Blot과 Immunoprecipitation에 적합. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 안정성을 제공. Translin 단백질 연구용으로 설계된 연구 전용 시약.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 150 to 200 of Human Translin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Phosphate/Tris citrate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Bovine and Orangutan
Target Information
Translin is a DNA-binding protein that specifically recognizes conserved target sequences at the breakpoint junctions of chromosomal translocations. Translin polypeptides form a multimeric structure responsible for DNA-binding activity. Recombination-associated motifs and translin-binding sites are found at recombination hotspots and may indicate breakpoints in genes fused by translocations. These binding activities may play a crucial role in chromosomal translocation in lymphoid neoplasms. Recent evidence suggests that, in combination with its binding partner Trax, Translin binds RNA and mediates trafficking in neurons.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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