
Thermo Fisher Scientific TSN Polyclonal Antibody
Rabbit polyclonal antibody targeting human Translin (TSN) for WB and IP applications. Unconjugated, liquid form with 1 mg/mL concentration. Predicted cross-reactivity with bovine and orangutan. For research use only.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 150 to 200 of Human Translin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Bovine and Orangutan
Target Information
Translin is a DNA-binding protein that specifically recognizes conserved target sequences at the breakpoint junctions of chromosomal translocations. Translin polypeptides form a multimeric structure responsible for DNA-binding activity.
Recombination-associated motifs and translin-binding sites are found at recombination hotspots and may indicate breakpoints in genes fused by translocations. These binding activities may play a key role in chromosomal translocation in lymphoid neoplasms.
Recent studies suggest that, in combination with its binding partner Trax, Translin binds RNA and mediates trafficking in neurons.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: A305-374A-M_TSN_Q15631-1_Rabbit.svg / A305-374A-M_TSN_Q15631-1_Rabbit_PDP.jpeg)
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