Thermo Fisher Scientific EPB41 Polyclonal Antibody
Rabbit polyclonal antibody targeting human EPB41 protein (aa 210–500). Validated for Western blot (1:500–1:2,000). Unconjugated liquid form, 0.95 mg/mL concentration. Stored at -20°C; for research use only.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 210–500 of human EPB41 (NP_0011594781) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.95 mg/mL |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2804985 |
Product Specific Information
Immunogen sequence:
MHCKVSLLDD TVYECVVEKH AKGQDLLKRV CEHLNLLEED YFGLAIWDNA TSKTWLDSAK EIKKQVRGVP WNFTFNVKFY PPDPAQLTED ITRYYLCLQL RQDIVAGRLP CSFATLALLG SYTIQSELGD YDPELHGVDY VSDFKLAPNQ TKELEEKVME LHKSYRSMTP AQADLEFLEN AKKLSMYGVD LHKAKDLEGV DIILGVCSSG LLVYKDKLRI NRFPWPKVLK ISYKRSSFFI KIRPGEQEQY ESTIGFKLPS YRAAKKLWKV CVEHHTFFRL TSTDTIPKSK F
- Positive Samples: Mouse brain, Mouse liver
- Cellular Location: Cytoplasm, Nucleus, Cell cortex, Cytoskeleton
Target Information
Elliptocytosis is a hematologic disorder characterized by elliptically shaped erythrocytes and varying degrees of hemolytic anemia. It is inherited as an autosomal dominant trait and results from mutations in genes encoding proteins of the red cell membrane skeleton. The form discussed here is linked to Rh blood group and caused by a defect in protein 4.1.
‘Rh-unlinked’ forms of elliptocytosis are caused by mutations in the alpha-spectrin, beta-spectrin, or band 3 genes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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