Thermo Fisher Scientific EIF2S1 Polyclonal Antibody
Rabbit polyclonal antibody targeting Human EIF2S1 (eIF2α). Validated for WB, ICC/IF, and IP applications. Supplied as liquid, unconjugated, preservative-free. Recommended storage at 2–8°C short term or –20°C long term.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:300–1:10,000 |
| Immunoprecipitation (IP) | 1–4 µL/mg of lysate |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to the C-terminus of Human EIF2S1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 1 month. For long-term storage, store at –20°C. |
| Shipping Conditions | Wet ice |
| RRID | AB_2788706 |
Product Specific Information
- This product is preservative-free.
- It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
- This antibody has specificity for Human eIF2α/EIF2S1.
Target Information
EIF2α (Eukaryotic translation initiation factor 2A) is a heterotrimer composed of three subunits (alpha, beta, and gamma).
This translation initiation factor promotes binding of initiator methionyl-tRNA to the 40S ribosome in an AUG-dependent manner to form the 43S pre-initiation complex.
The polypeptide can be phosphorylated by stress-activated protein kinases. Phosphorylated EIF2A inhibits EIF2B activity and prevents guanine nucleotide exchange.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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