Thermo Fisher Scientific K-cadherin Polyclonal Antibody
Human K-cadherin을 인식하는 Rabbit Polyclonal Antibody로, IHC(P)에서 1:50~1:200 희석 배율로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS 및 40% glycerol buffer에 보관. 세포 간 결합 연구 및 신장 조직 연구에 적합.
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Thermo Fisher Scientific K-cadherin Polyclonal Antibody
Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Protein corresponding to Human K-cadherin. Recombinant protein control fragment (Product #RP-90120). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.10 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2856128 |
Product Specific Information
Immunogen sequence:
LDRETLLWHN ITVIATEINN PKQSSRVPLY IKVLDVNDNA PEFAEFYETF VCEKAKADQL IQTLHAVDKD DPYSGHQFSF SLAPEAASGS NFTIQDNKDN TAGILTRKNG YNRHEMSTYL LP
Target Information
Cadherins constitute a family of transmembrane glycoproteins involved in Ca²⁺-dependent cell-cell interactions. The members of this family are differentially expressed in various tissues and function in the maintenance of tissue integrity and morphogenesis.
Cadherins are divided into type I and type II subgroups.
- Type I cadherins: E-cadherin (cadherin-1), N-cadherin (cadherin-2), P-cadherin (cadherin-3), R-cadherin (cadherin-4)
- Type II cadherins: K-cadherin (cadherin-6), OB-cadherin (cadherin-11)
Cadherin-6 is expressed in the proximal tubule epithelium of the kidney, from which most renal cell carcinomas are derived.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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