Thermo Fisher Scientific RAB27A Polyclonal Antibody
RAB27A 단백질을 검출하기 위한 Rabbit Polyclonal 항체. Western blot, IHC, ICC/IF에 사용 가능. 인간, 마우스, 랫트 반응성. Affinity chromatography로 정제된 액상 형태로, PBS/glycerol buffer에 보관. 연구용 전용 제품.
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- PA5102522
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human RAB27A (Accession P51159), corresponding to amino acid residues E186–C221 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2851924 |
Product Specific Information
This antibody detects endogenous levels of total RAB27A.
Target Information
The protein encoded by RAB27A belongs to the small GTPase superfamily, Rab family. It is a membrane-bound protein involved in protein transport and small GTPase-mediated signal transduction. Mutations in this gene are associated with Griscelli syndrome type 2. Alternative splicing occurs at this locus, resulting in four transcript variants encoding the same protein. RAB27A plays a crucial role in cytotoxic granule exocytosis in lymphocytes and is required for both granule maturation and granule docking/priming at the immunologic synapse.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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