Thermo Fisher Scientific Caspase 7 (Cleaved Asp198) Polyclonal Antibody
Cleaved Caspase-7 (Asp198) 인식 폴리클로날 항체로 인간, 마우스, 원숭이, 랫트 반응성. Western blot 및 Immunoprecipitation에 적합. Protein A 정제, 액상 형태, -20°C 보관. 전장 Caspase-7 및 기타 Caspase와 비교차 반응.
- 카탈로그번호
- PA517909
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Immunoprecipitation (IP)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino-terminal residues surrounding Asp198 in human caspase-7 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 135 µg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 100 µg/mL BSA, 0.15M NaCl, 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10978469 |
Product Specific Information
- It is not recommended to aliquot this antibody.
- This antibody is not cross-reactive with full length caspase-7 or with other caspases.
Target Information
Caspase 7 is a member of the cysteine protease family divided into apoptotic and inflammatory subfamilies.
Apoptotic caspases include initiator and executioner types; Caspase 7 functions as an executioner caspase, cleaving cellular substrates during apoptosis.
It shares homology with Caspases 1 and 3 and the C. elegans protein CED-3.
Alternative splicing of Caspase-7 mRNA generates three isoforms, and its activity can be inhibited by XIAP expression.
Diseases associated with CASP7 include Type 1 Diabetes Mellitus 17 and Aleutian Mink Disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: PA5-17909_Caspase_7_Cleaved_Asp198_P55210-1_Rabbit.svg, PA5-17909_Caspase_7_Cleaved_Asp198_P55210-1_Rabbit_PDP.jpeg)
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