Thermo Fisher Scientific NPTX2 Polyclonal Antibody
Rabbit polyclonal antibody targeting Human NPTX2 for WB and IHC applications. Recognizes neuronal pentraxin 2 involved in synaptogenesis and Parkinson’s disease pathways. Supplied as unconjugated liquid, purified by antigen affinity chromatography, and...
- 카탈로그번호
- PA530105
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:100–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to amino acids 187–431 of Human NPTX2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.25 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term; for long term storage, store at -20°C avoiding freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2547579 |
Product Specific Information
- Recommended positive control: Jurkat cells
- Predicted reactivity: Mouse (98%), Rat (98%), Guinea pig (95%)
- Store as a concentrated solution; centrifuge briefly before opening the vial.
Target Information
Neuronal pentraxin (NPTX) 2 is a member of the pentraxin family with high homology to NPTX1. Unlike NPTX1, NPTX2 is expressed in testes, pancreas, liver, heart, skeletal muscle, and brain. It possesses lectin properties common to the pentraxin family, promotes neurite outgrowth, and is rapidly regulated by neuronal activity. NPTX1 and NPTX2 form heterocomplexes contributing to excitatory synaptogenesis. NPTX2 is highly upregulated in Parkinsonian substantia nigra and localizes to Lewy bodies and neurites, implicating it in Parkinson’s disease pathway dysregulation.
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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