Thermo Fisher Scientific TLE1 Recombinant Rabbit Monoclonal Antibody (TLE1, 2946R)
TLE1 단백질을 표적으로 하는 Thermo Fisher Scientific의 재조합 토끼 단클론 항체. 인체 시료에 반응하며 IHC(P) 실험에 적합. 고순도 Protein A/G 정제, 액상 형태로 제공. 연구용으로만 사용 가능.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | TLE1, 2946R |
| Immunogen | Recombinant human TLE1 fragment (aa 175–338) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Immunohistochemistry (PFA fixed): incubate antibody for 30 min at room temperature.
- Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA (pH 9.0) for 45 min at 95°C, followed by cooling at room temperature for 20 min.
Target Information
Transcriptional corepressor that binds to various transcription factors.
Inhibits NF-kappa-B-regulated gene expression and transcriptional activation mediated by FOXA2, CTNNB1, and TCF family members in Wnt signaling.
The effects of full-length TLE family members may be modulated by association with dominant-negative AES.
Shows unusual coactivator function for ESRRG.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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