Thermo Fisher Scientific POLR3K Polyclonal Antibody, MaxPab

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:1,000

Immunocytochemistry (ICC/IF)

• Tested Dilution: 10 µg/mL

Product Specifications

Product Specific Information

Sequence of this protein is as follows:
MLLFCPGCGN GLIVEEGQRC HRFACNTCPY VHNITRKVTN RKYPKLKEVD DVLGGAAAWE NVDSTAESCP KCEHPRAYFM QLQTRSADEP MTTFYKCCNA QCGHRWRD

Target Information

Eukaryotes produce three distinct classes of RNA polymerase: Pol I, II, and III.
Each polymerase synthesizes a different class of RNA.
RNA polymerase III (Pol III) transcribes 5S rRNA genes and all tRNA genes.

POLR3K, also known as DNA-directed RNA polymerase III subunit RPC11, is a 108 amino acid nuclear protein and one of the seventeen subunits comprising Pol III.
POLR3K functions as a DNA-dependent RNA polymerase that uses ribonucleoside triphosphates to catalyze DNA transcription into RNA.
The POLR3K gene is located on human chromosome 16, which encodes over 900 genes across approximately 90 million base pairs and is associated with various genetic disorders.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.