
Thermo Fisher Scientific RAB23 Polyclonal Antibody, MaxPab
RAB23 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, Western blot에 최적화되어 있습니다. 인간 및 마우스 반응성이 있으며 액상 형태로 제공됩니다. 친화 크로마토그래피로 정제되어 연구용 단백질 분석에 적합합니다.
- 카탈로그번호
- H00051715-D01P
- 판매단위
- pk
카탈로그
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Applications
- Western Blot (WB): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | RAB23 (NP_057361.3, 1–237 a.a) full-length human protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MLEEDMEVAI KMVVVGNGAV GKSSMIQRYC KGIFTKDYKK TIGVDFLERQ IQVNDEDVRL MLWDTAGQEE FDAITKAYYR GAQACVLVFS TTDRESFEAV SSWREKVVAE VGDIPTVLVQ NKIDLLDDSC IKNEEAEALA KRLKLRFYRT SVKEDLNVNE VFKYLAEKYL QKLKQQIAED PELTHSSSNK IGVFNTSGGS HSGQNSGTLN GGDVINLRPN KQRTKKNRNP FSSCSIP
Target Information
The Ras-related superfamily of guanine nucleotide binding proteins includes the R-Ras, Rap, Ral/Rec, and Rho/Rab subfamilies. Rab proteins play a key role in endocytosis and biosynthetic protein transport, facilitating movement of carrier vesicles from the endoplasmic reticulum to the Golgi complex and secretory vesicles.
Rab23 (HSPC137) is a 237 amino acid member of the Rab family localized to the cytoplasmic side of the cell membrane. It is involved in intracellular protein transport and signal transduction mediated by small GTPases. Mutations in the Rab23 gene may cause Carpenter syndrome (ACPS2), characterized by obesity, cardiac defects, polysyndactyly, and craniosynostosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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