Thermo Fisher Scientific RAB23 Polyclonal Antibody, MaxPab

Applications

• Western Blot (WB): 1:500–1:1,000

Product Specifications

Product Specific Information

Sequence of this protein is as follows:
MLEEDMEVAI KMVVVGNGAV GKSSMIQRYC KGIFTKDYKK TIGVDFLERQ IQVNDEDVRL MLWDTAGQEE FDAITKAYYR GAQACVLVFS TTDRESFEAV SSWREKVVAE VGDIPTVLVQ NKIDLLDDSC IKNEEAEALA KRLKLRFYRT SVKEDLNVNE VFKYLAEKYL QKLKQQIAED PELTHSSSNK IGVFNTSGGS HSGQNSGTLN GGDVINLRPN KQRTKKNRNP FSSCSIP

Target Information

The Ras-related superfamily of guanine nucleotide binding proteins includes the R-Ras, Rap, Ral/Rec, and Rho/Rab subfamilies. Rab proteins play a key role in endocytosis and biosynthetic protein transport, facilitating movement of carrier vesicles from the endoplasmic reticulum to the Golgi complex and secretory vesicles.
Rab23 (HSPC137) is a 237 amino acid member of the Rab family localized to the cytoplasmic side of the cell membrane. It is involved in intracellular protein transport and signal transduction mediated by small GTPases. Mutations in the Rab23 gene may cause Carpenter syndrome (ACPS2), characterized by obesity, cardiac defects, polysyndactyly, and craniosynostosis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.