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Thermo Fisher Scientific LAMP1 Monoclonal Antibody (H4A3), PE

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LAMP1 (CD107a) 단백질을 인식하는 마우스 단클론 항체로, PE 형광 표지되어 있습니다. 인간, 마우스, 비인간 영장류 시료에 반응하며, 유세포 분석(Flow Cytometry)에 적합합니다. 액상 형태로 제공되며 4°C에서 암소 보관합니다.

카탈로그번호: A15798
브랜드: Thermo Fisher Scientific
카테고리: Monoclonal Antibodies
판매단위: pk

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마지막 업데이트 2025. 08. 04. 오전 08:25

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Thermo Fisher Scientific A15798 LAMP1 Monoclonal Antibody (H4A3), PE 100 tests pk판매 단위 pk ·

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360,700원VAT 포함 396,770원

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Thermo Fisher Scientific · Thermo Fisher Scientific LAMP1 Monoclonal Antibody (H4A3), PE

Applications

Flow Cytometry (Flow): 4 µL/1×10⁶ cells
View 2 publications

Product Specifications

항목	내용
Species Reactivity	Human, Mouse, Non-human primate
Published Species	Human
Host / Isotype	Mouse / IgG1, kappa
Class	Monoclonal
Type	Antibody
Clone	H4A3
Immunogen	Human adherent peripheral blood cells
Conjugate	PE (R-Phycoerythrin)
Excitation / Emission Max	565 / 576 nm
Form	Liquid
Purification	Size-exclusion chromatography
Storage Buffer	PBS, pH 7.4, with 0.2% BSA
Contains	15 mM sodium azide
Storage Conditions	4°C, store in dark, DO NOT FREEZE
Shipping Conditions	Ambient (domestic); Wet ice (international)
RRID	AB_2534576

Additional Formats

Product Specific Information

This antibody recognizes an extracellular/luminal epitope of CD107a, an approximately 100–120 kDa glycoprotein expressed mainly on lysosomal membranes, and also on the plasma membrane.

Target Information

LAMP1 (CD107a, lysosome-associated membrane protein-1) is a major component of the lysosomal membrane. Together with LAMP2, it contributes to lysosome biogenesis and fusion with phagosomes. LAMP1 is a heavily glycosylated type I integral membrane protein with 18 N-linked glycosylation sites, a single transmembrane domain, and a short cytosolic tail.
Upon cell activation, LAMP1 translocates to the plasma membrane via a tyrosine-based motif (YXXI). Mutations affecting this motif alter lysosomal localization, causing cycling between plasma membrane and endosomes.
Cell surface LAMP1 and LAMP2 promote adhesion of PBMCs to vascular endothelium, suggesting a role in inflammation. Increased LAMP1 expression is observed in neurons and glial cells near senile plaques in Alzheimer’s disease, and in immune cells during acute thymic involution. LAMP1 serves as a useful marker for mast cell activation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.