Thermo Fisher Scientific CD7 Polyclonal Antibody
Thermo Fisher Scientific의 CD7 Polyclonal Antibody는 인간 및 랫트 시료에 반응하는 고순도 항체로, T세포 및 NK세포 연구에 적합합니다. Western blot과 Flow cytometry에 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. 장기 보관 시 -20°C에서 안정적으로 유지됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Flow Cytometry (Flow)
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein of human CD7 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C avoiding freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2803769 |
Product Specific Information
- Purity is >95% by SDS-PAGE.
Target Information
CD7 (gp40, Leu9) is a 40 kDa member of the immunoglobulin gene superfamily. The N-terminal amino acids (1–107) are highly homologous to Ig kappa-L chains, while the C-terminal extracellular domain is proline-rich and may form a stalk projecting the Ig domain.
CD7 is expressed on most immature and mature T-lymphocytes, T cell leukemia cells, natural killer cells, a subset of normal B cells, and malignant B cells.
Cross-linking surface CD7 enhances T cell and NK cell activity, influencing calcium flux, adhesion molecule expression, cytokine secretion, and proliferation.
CD7 directly associates with phosphoinositol 3'-kinase, and ligation induces production of D-3 phosphoinositides and tyrosine phosphorylation.
CD7 expression serves as an important marker in leukemia diagnostics.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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