Thermo Fisher Scientific IL12RB1 Monoclonal Antibody (OTI1A6), TrueMAB
IL12RB1 단백질을 인식하는 Mouse IgG1 단클론 항체로, Western blot에 적합합니다. 인간 IL12RB1(aa 33-283) 재조합 단백질을 항원으로 제작되었으며, 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB): Tested dilution 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1A6 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 33–283 of human IL12RB1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by IL12RB1 is a type I transmembrane protein belonging to the hemopoietin receptor superfamily. It binds interleukin 12 with low affinity and forms part of the IL12 receptor complex. The protein forms a disulfide-linked oligomer required for IL12 binding activity. Coexpression with IL12RB2 leads to high-affinity IL12 binding and reconstitution of IL12-dependent signaling. Deficiency in expression may cause immunodeficiency associated with severe mycobacterial and Salmonella infections. Two alternatively spliced transcript variants encoding distinct isoforms have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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