Thermo Fisher Scientific NACAD Polyclonal Antibody
Thermo Fisher Scientific의 NACAD 폴리클로날 항체로 인간 NACAD 단백질을 특이적으로 검출. Western blot과 Immunocytochemistry에 적합. 고순도 친화 크로마토그래피 정제. 액상 형태로 안정적인 저장 (-20°C) 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
- Publications: [참조 없음]
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
- Publications: [참조 없음]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human NACAD (Accession O15069), corresponding to amino acid residues E41–P91 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2851125 |
Product Specific Information
Antibody detects endogenous levels of total NACAD.
Target Information
May prevent inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER).
May bind to nascent polypeptide chains as they emerge from the ribosome and block their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER.
May also reduce the inherent affinity of ribosomes for protein translocation sites in the ER membrane (M sites).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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