Thermo Fisher Scientific PRDX3 Recombinant Rabbit Monoclonal Antibody (14E2)
PRDX3 단백질을 인식하는 토끼 리콤비넌트 모노클로날 항체로, Western blot, IHC, ICC/IF, Flow cytometry, ELISA 등 다양한 응용에 사용 가능. 높은 특이성과 재현성을 제공하며, 인간 시료에 반응. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| Flow Cytometry (Flow) | 1:50–1:200 |
| ELISA | Assay-dependent |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 14E2 |
| Immunogen | A synthesized peptide derived from human PRDX3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.25 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Wet ice |
| RRID | AB_3092490 |
Target Information
Peroxiredoxin (Prx) is a growing peroxidase family whose mammalian members are known to be involved in cell proliferation, differentiation, and apoptosis. Many isoforms (about 50 proteins) are grouped according to amino acid sequence homology and contain active site cysteine residues with thiol-specific antioxidant activity. Mammalian Prx consists of six different members grouped into typical 2-Cys, atypical 2-Cys, and 1-Cys Prx. Except for Prx VI (1-Cys subgroup), the other five 2-Cys Prx isotypes possess thioredoxin-dependent peroxidase (TPx) activity utilizing thioredoxin, thioredoxin reductase, and NADPH as a reducing system. Mammalian Prxs are 20–30 kDa in size and vary in subcellular localization: Prx I, II, and VI in cytosol; Prx III in mitochondria; Prx IV in ER and secretion; Prx V shows complex distribution including peroxisome, mitochondria, and cytosol.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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