Thermo Fisher Scientific ARL2BP Monoclonal Antibody (OTI1F8), TrueMAB

Applications

Western Blot (WB)

• Tested Dilution: 1:2,000

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 1:150

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

ADP-ribosylation factor (ARF)-like proteins (ARLs) are a distinct subgroup of the ARF family of RAS-related GTPases.
The ARL2BP protein binds to ARL2•GTP with high affinity but does not interact with ARL2•GDP, activated ARF, or RHO proteins.
Its lack of membrane association upon ARL2 activation suggests a unique functional role distinct from ARFs.
ARL2BP is considered the first ARL2-specific effector identified due to its interaction with ARL2•GTP but absence of ARL2 GTPase-activating activity.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.