Thermo Fisher Scientific ETV1 Polyclonal Antibody
ETV1 단백질을 인식하는 Rabbit Polyclonal 항체로, WB 및 ICC/IF에 사용 가능. 인간과 생쥐 시료에서 반응하며, 액상 형태로 공급. Affinity chromatography로 정제되어 높은 특이성과 재현성을 제공.
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- PA5101118
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human ETV1 (Accession P50549), corresponding to amino acid residues G3–L53 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2850562 |
Product Specific Information
Antibody detects endogenous levels of total ER81.
Target Information
ETV1 (ets variant gene 1):
Several members of the Ets gene family encode sequence-specific DNA binding proteins that recognize DNA sequences with a centrally located 5'-GGAA-3' element. All Ets proteins recognize this central core sequence but interact with unique flanking sequences.
ER81 (also designated ETV1) binds the motif 5'-CGGAA/T-3' and is highly expressed in brain, testis, lung, and heart. It is moderately expressed in spleen, pancreas, colon, and small intestine. During development, ER81 displays unique expression patterns suggesting an important role in organogenesis. ERK-1 activates ER81 transcriptional activity, while MAPKAP kinase 2 inhibits ER81.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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